Jesus gives the clearest direction
Jesus was asked about marriage in the resurrection, after the Sadducees raised a complicated case involving a widow and seven brothers. His answer was that those raised from the dead will not marry as people do now, but will be like the angels of God in heaven (Matthew 22:23-27; Matthew 22:30).
That comparison does not answer every imaginable question about angels. Still, it matters. Marriage, family lines, and bearing children belong to earthly human life. Jesus points to angels as living differently.
Scripture describes angels as servants God sends to carry out his purposes for those who will inherit salvation (Hebrews 1:14). They worship God, obey his commands, and bring messages, but the Bible does not present them as a species that builds families or produces descendants.
For in the resurrection they neither marry, nor are given in marriage, but are as the angels of God in heaven.
Why Genesis 6 raises questions
Genesis 6:1-4 is the passage behind most of the debate. It says that the sons of God took daughters of men as wives, and it mentions the Nephilim. Some Christians understand the sons of God to be fallen angels, since the same expression appears for heavenly beings in Job 1:6 and Job 2:1.
Others understand the sons of God as faithful human descendants of Seth who intermarried with women from ungodly families. They note that Genesis is tracing human sin, violence, and corruption in the lead-up to the flood.
Both readings have been defended by sincere Bible readers. But Genesis 6 never directly says, “angels reproduced”, so it is wise not to make a firm doctrine from details the passage leaves unstated.
And it came to pass, when men began to multiply on the face of the earth, and daughters were born unto them, That the sons of God saw the daughters of men that they were fair; and they took them wives of all which they chose. And the Lord said, My spirit shall not always strive with man, for that he also is flesh: yet his days shall be an hundred and twenty years. There were giants in the earth in those days; and also after that, when the sons of God came in unto the daughters of men, and they bare children to them, the same became mighty men which were of old, men of renown.
Rebellious angels are real
The Bible does teach that some angels rebelled. Jude says they did not keep their proper place and are being held for judgement (Jude 1:6). Peter likewise refers to angels who sinned and were not spared (2 Peter 2:4).
Yet neither writer says these angels married, had sexual relationships, or produced children. Their rebellion should not be used to supply information Scripture does not give.
A careful biblical answer
Angels are created beings, not divine rivals or mysterious human-like clans. Psalm 148 calls them to praise their Creator, and says the Lord commanded and they were created (Psalm 148:2-5). At times they appeared in a recognisably human form, as when visitors came to Abraham (Genesis 18:1-2). But appearing human is not the same as having a human nature or biology.
So the best answer is that Scripture gives no clear basis for believing angels reproduce. Jesus’ words point in the opposite direction, and the one difficult passage often raised, Genesis 6, remains uncertain. Read it carefully, but hold conclusions about its disputed details with humility.
Are they not all ministering spirits, sent forth to minister for them who shall be heirs of salvation?